PYK2(Phospho Tyr579) Polyclonal Antibody, 100ul Cell Proliferation Polymorphisms that affect the normal

Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis

Defects in this gene are a cause of childhood cancer retinoblastoma (RB)

The encoded protein associates with the plasma membrane and may function as a signal transducer

stimulates dissociation of TOP1 from DNA after cleavage and enhances its jumping between separate DNA helices

PYK2(Phospho Tyr579) Polyclonal Antibody, 100ul Cell Proliferation Polymorphisms that affect the normalThis gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and