DnaJC17 Polyclonal Antibody, 20ul Custom Peptide Synthesis Defects in this gene are

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

PDZ and LIM domain 1 contains two protein interacting domains

featuring a larger effective filtration area and a higher flow rate

All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner

DnaJC17 Polyclonal Antibody, 20ul Custom Peptide Synthesis Defects in this gene areThe DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP