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EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator The encoded protein promotes attachment

SKU: 37847260097

4.4
EUR135.00 EUR175.00

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EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator The encoded protein promotes attachmentThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

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Description

The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin

the encoded protein binds to the putative leucine zipper domain of macroH2A1

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily

Several transcript variants encoding different isoforms have been found for SHC1

EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator The encoded protein promotes attachmentThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

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