TLR8 Polyclonal Antibody, 100ul Miscellaneous PIAS3 encodes a member of

PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators

EF3 subfamily

Numerous pseudogenes have been reported for this gene

This protein is involved in native immunity against invading pathogens

TLR8 Polyclonal Antibody, 100ul Miscellaneous PIAS3 encodes a member ofThe protein encoded by this gene is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of