MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein component

MED8 encodes a protein component of the mediator complex

Members of this family are anti-proliferative factors that have the potential to regulate cell growth

It is expressed in the tissue and circulating myeloid leukocytes

This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics

MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript