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GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence The protein encoded by this

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GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence The protein encoded by thisThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease| Yme1p

Required for stabilization of KCNH1 channels at the cell membrane (PubMed: 23144454)

Mutations in this gene may be associated with osteoarthritis in human patients

Read-through transcription also exists between this gene and the downstream melanoma antigen family A

GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence The protein encoded by thisThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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