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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and overexpressed in colon tumors

SKU: 38622778696

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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and overexpressed in colon tumorsThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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Description

and overexpressed in colon tumors

and also as a coactivator of NF-kappaB-mediated transcription

CLCs are involved in membrane potential stabilization

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta interacts with IRS1 protein

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and overexpressed in colon tumorsThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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