Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein has been

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct

This gene is present in a gene cluster with other members of the ADAM family on chromosome 8

hence plays a key role in the physiology of adrenergic neurons

Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression

Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein has beenStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which