Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing it is now thought to

it is now thought to be a non-opioid receptor

subcellular location:Expressed diffusely throughout the nucleus

This protein mediates the signals of the bone morphogenetic proteins (BMPs)| which are involved in a range of biological activities including cell growth| apoptosis| morphogenesis| development and immune responses

Translocations between MLF1 and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia

Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing it is now thought toThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.