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Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips where it causes a nonconservative

SKU: 39312955760

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Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips where it causes a nonconservativeSFXN4 encodes a member of the sideroflexin family. The sideroflexin 4 is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene.

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Description

where it causes a nonconservative amino acid substitution

contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 Lys-9 trimethylation

The related mouse gene is expressed only in oocytes

Mutations in this gene have been associated with geroderma osteodysplastica

Sideroflexin-4 Polyclonal Antibody, 20ul Pipette Micro Tips where it causes a nonconservativeSFXN4 encodes a member of the sideroflexin family. The sideroflexin 4 is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene.

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