IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos subunit:Homodimer and homotetramer via the

subunit:Homodimer and homotetramer via the coiled coil regions

tyrosine sulfation

an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-8

The protein encoded by this gene belongs to the actin family of proteins

IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos subunit:Homodimer and homotetramer via theInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.