GCM1 Rabbit Polyclonal Antibody, 20ul Bacterial Expression but down regulated in ovarian

but down regulated in ovarian cancer cell lines and primary carcinomas

Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation| while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease

and a single guanylate kinase-like (GUK)-domain

The DHR-2 domain is necessary for the GEF activity

GCM1 Rabbit Polyclonal Antibody, 20ul Bacterial Expression but down regulated in ovarianThis gene encodes a DNA binding protein with a gcm motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM motif (A G)CCCGCAT a novel sequence among known targets of DNA binding proteins. The N terminal DNA binding domain confers the unique DNA binding activity of this protein.