p53(Phospho Ser378) Polyclonal Antibody, 100ul Sealing Film The structure of the protein

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins

Reduced expression of this protein has been implicated in cardiomyopathies

The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development

This gene is located in the male-specific region of the Y chromosome

p53(Phospho Ser378) Polyclonal Antibody, 100ul Sealing Film The structure of the proteinThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.