p57 Monoclonal Antibody, 100ul Plasma ADAM family members are type

ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules

Alternatively spliced transcript variants encoding distinct isoforms have been found for GOSR1

This gene encodes alpha-enolase

The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis

p57 Monoclonal Antibody, 100ul Plasma ADAM family members are typeThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.