ARAP1 Polyclonal Antibody, 100ul Immunology Mutations in this gene are

Mutations in this gene are associated with hypogonadotropic hypogonadism

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5|10-methylene tetrahydrofolate

HIV-1 Tat protein was found to interact with this protein and cyclin T

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

ARAP1 Polyclonal Antibody, 100ul Immunology Mutations in this gene areThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a