MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene result

Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis

The protein encoded by FGFRL1 (fibroblast growth factor receptor-like 1) is a member of the fibroblast growth factor receptor (FGFR) family

and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription

This gene is a candidate gene for RET-associated diseases

MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene resultThis gene encodes a member of the P type lectin family. P type lectins play a critical role in lysosome function through the specific transport of mannose 6 phosphate containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene