PTPRT Polyclonal Antibody, 100ul Shaker&Mixing Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants for CDH19

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

three EGF homology domains and three fibronectin type III domains in their extracellular regions

The protein is involved in repressing and activating a diverse number of promoters

PTPRT Polyclonal Antibody, 100ul Shaker&Mixing Alternative splicing results in multipleThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor type PTP. The extracellular region