PLXA3 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis Methylation of the promoter of

Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML)

It may be part of a physiologic ligand-receptor complex involved in T-cell activation

see PSG1 (MIM 176390)

it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA

PLXA3 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis Methylation of the promoter ofThis gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression.