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TNF Alpha-IP 2 Polyclonal Antibody, 50ul Deep Well Plates protein FADD can be recruited

SKU: 45794884462

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TNF Alpha-IP 2 Polyclonal Antibody, 50ul Deep Well Plates protein FADD can be recruitedTNFAIP2 (TNF alpha induced protein 2) was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that TNFAIP2 may be a retinoic acid target gene in acute promyelocytic leukemia.

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Description

protein FADD can be recruited by TNFRSF6/Fas-receptor

eight LRR (leucine-rich) repeats and one LRRCT domain

The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid glands

and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation

TNF Alpha-IP 2 Polyclonal Antibody, 50ul Deep Well Plates protein FADD can be recruitedTNFAIP2 (TNF alpha induced protein 2) was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that TNFAIP2 may be a retinoic acid target gene in acute promyelocytic leukemia.

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