Histone H3 (Di-Methyl-K80) Polyclonal Antibody, 100ul Drying & Desiccation Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding the same protein have been described

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

In addition to being critical for mRNA splicing

This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase

Histone H3 (Di-Methyl-K80) Polyclonal Antibody, 100ul Drying & Desiccation Alternatively spliced transcript variants encodingHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin