CD58 Polyclonal Antibody, 100ul[BT-AP01842] Filtration Mediator complex subunit 17 encoded

Mediator complex subunit 17 encoded by MED17 is a subunit of the CRSP (cofactor required for SP1 activation) complex

Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family

2001 [PubMed 12063393])

Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene

CD58 Polyclonal Antibody, 100ul[BT-AP01842] Filtration Mediator complex subunit 17 encodedThe product of CLDN19 belongs to the claudin family. It plays a major role in tight junction specific obliteration of the intercellular space, through calcium independent cell adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe