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DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging hematopoietic differentiation

SKU: 4806860377

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DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging hematopoietic differentiationThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome

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Description

hematopoietic differentiation

The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus

Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity)

Plays an essential role in autophagy

DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging hematopoietic differentiationThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome

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