LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation The receptor is comprised of

The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3)

1 Units/μL of yeast-based activity in a convenient 500 μL package

Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer

Mutations in this gene are associated with an increased susceptibility to viral

LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation The receptor is comprised ofLecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all trans retinol into all trans retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.