HLAG Polyclonal Antibody, 50ul Molecular Biology Genome-wide association studies in some

Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis

Alternative splicing yields two isoforms that differ in abundance and expression patterns

HLA-C belongs to the HLA class I heavy chain paralogues

Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrop

HLAG Polyclonal Antibody, 50ul Molecular Biology Genome-wide association studies in someHLA G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide,