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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes including

SKU: 48852137066

4.2
PLN162.00 PLN191.00

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

which activates other proenzymes including chymotrypsinogen and procarboxypeptidases

Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function

and lowest expression in pancreas

|Contains 1 protein kinase domain

PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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