FADD(Phospho Ser191) Polyclonal Antibody, 50ul Mechanical Pipette Mutations in this gene may

Mutations in this gene may be associated with adult-onset sensorimotor neuropathy| pigmentary retinopathy| and adrenomyeloneuropathy due to defects in bile acid synthesis

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex

resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis

An important paralog of this gene is TJAP1

FADD(Phospho Ser191) Polyclonal Antibody, 50ul Mechanical Pipette Mutations in this gene mayThe Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C terminal death domain, this protein can be recruited by TNFRSF6 Fas receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10 TRAIL receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors