Akt1 Polyclonal Antibody, 100ul[BT-AP00347] Enzyme Activity Assays The encoded protein may act

The encoded protein may act as a co-factor of TEF-1 regulated gene expression during skeletal muscle development

As a result of the gene translocation

The protein encoded by this gene shares the synapsin family domain model

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

Akt1 Polyclonal Antibody, 100ul[BT-AP00347] Enzyme Activity Assays The encoded protein may actThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a