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FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 20ul 3D Culture The protein is weakly similar

SKU: 50993670274

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FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 20ul 3D Culture The protein is weakly similardisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.

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Description

The protein is weakly similar to transposase-like proteins in human and mouse

that may share one or more domains in common

which is part of the response to intracellular nitric oxide

The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4

FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 20ul 3D Culture The protein is weakly similardisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.

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