TBX15/18 Polyclonal Antibody, 50ul Protein Modification A splice variant of this

A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway

Mutations in this gene may be associated with X-linked obesity

This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine| aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif)

An important paralog of this gene is ERAP2

TBX15/18 Polyclonal Antibody, 50ul Protein Modification A splice variant of thisTBX18 codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA binding T box domain and is divided into five sub families based on sequence conservation in this domain. The T box transcription factor TBX18 belongs to the vertebrate specific Tbx1 sub family. The protein acts as a transcriptional repressor by antagonizing