Vimentin Polyclonal Antibody, 100ul[BT-AP09528] Centrifuges Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been noted for this gene

Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2)

are found in amniotic fluid

DVL2 encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein

Vimentin Polyclonal Antibody, 100ul[BT-AP09528] Centrifuges Alternatively spliced transcript variants encodingVIM encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. Vimentin encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low density lipoprotein (LDL) derived cholesterol from a lysosome to the