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CD63 Polyclonal Antibody, 50ul[BT-AP02241] Vessels Two similar genes are located

SKU: 51660404450

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CD63 Polyclonal Antibody, 50ul[BT-AP02241] Vessels Two similar genes are locatedDPYSL2 encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. DPYSL4 has been implicated in multiple neurological disorders,

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Description

Two similar genes are located nearby on chromosome 7q22 and a pseudogene is found on chromosome 7p13

The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele

It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway

Diseases associated with CDK15 include amyotrophic lateral sclerosis 2

CD63 Polyclonal Antibody, 50ul[BT-AP02241] Vessels Two similar genes are locatedDPYSL2 encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. DPYSL4 has been implicated in multiple neurological disorders,

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