Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in this gene cause

Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex

PEAK1 (pseudopodium enriched atypical kinase 1) encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family

Within leukocyte population more abundant expression in neutrophils and eosinophils

Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed

Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in this gene causeThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.