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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Tango1 subfamily

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Tango1 subfamily

Name: Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Tango1 subfamily
Brand: matisco.be
SKU: 52280033989
Price: 185.00 USD
Availability: InStock
Rating: 4.0405 (14 reviews)

SKU: 52280033989

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USD185.00 USD212.00

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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Tango1 subfamilyThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

Tango1 subfamily

PTM:Phosphorylated upon DNA damage

The protein encoded by PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis

The product of this gene binds to chemokine receptors CCR4 and CCR8

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