DCTN4 Polyclonal Antibody, 100ul Immunoassays 5 mL micro centrifuge tubes

5 mL micro centrifuge tubes

The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system

PML is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL)

May exert this function by promoting GLI1 nuclear localization

DCTN4 Polyclonal Antibody, 100ul Immunoassays 5 mL micro centrifuge tubesCould have a dual role in dynein targeting and in ACTR1A Arp1 subunit of dynactin pointed end capping. Could be involved in ACTR1A pointed end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,Belongs to the dynactin subunit 4 family.,subcellular location: Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization