IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Histone deacetylase 5 by HDAC5

Histone deacetylase 5 by HDAC5 belongs to the class II histone deacetylase/acuc/apha family

exons 2 and 3 encode the alpha1 and alpha2 domain

adds and removes ubiquitin

This heterodimer binds E-box enhancer elements upstream of Period (PER1| PER2| PER3) and Cryptochrome (CRY1| CRY2) genes and activates transcription of these genes

IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Histone deacetylase 5 by HDAC5This gene encodes an intracellular receptor for inositol 1 4 5 trisphosphate. Upon stimulation by inositol 1 4 5 trisphosphate this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15 a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.