Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Mutations in this gene have

Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency

probable scaffold protein that may be involved in mRNA transport

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis

Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Mutations in this gene haveThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).