p53 (Acetyl Lys382) Polyclonal Antibody, 50ul Electronic Pipette Acts as a transcriptional coactivator

Acts as a transcriptional coactivator of serum response factor (SRF)

and these receptors have been shown to activate phospholipase C

It possesses histone deacetylase activity and represses transcription when tethered to a promoter

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

p53 (Acetyl Lys382) Polyclonal Antibody, 50ul Electronic Pipette Acts as a transcriptional coactivatorTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative