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PEA-15 Polyclonal Antibody, 20ul[BT-AP07044] Hybridoma Antibody Sequencing a potent vasodilator and inhibitor

SKU: 57766942217

4.1
USD111.00 USD149.00

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PEA-15 Polyclonal Antibody, 20ul[BT-AP07044] Hybridoma Antibody Sequencing a potent vasodilator and inhibitorPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

a potent vasodilator and inhibitor of platelet aggregation

Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase

Functions also as a receptor for aldosterone mediating rapid regulation of vascular contractibility through the PI3K/ERK signaling pathway

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PEA-15 Polyclonal Antibody, 20ul[BT-AP07044] Hybridoma Antibody Sequencing a potent vasodilator and inhibitorPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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