PAI-3 Polyclonal Antibody, 50ul Modification Enzymes cofactor:Binds 1 sodium ion per

cofactor:Binds 1 sodium ion per subunit

and is implicated in the regulation of integrin signaling

This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene

Also CD63 has been associated with tumor progression

PAI-3 Polyclonal Antibody, 50ul Modification Enzymes cofactor:Binds 1 sodium ion perPAI 1, PAI 2 and PAI 3 (plasminogen activator inhibitor 1, 2 and 3) are members of the serpin serine proteinase inhibitor family. PAI 1 and PAI 2 regulate uPA (urokinase type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms.