NCoA-5 Polyclonal Antibody, 100ul Apoptosis & Autophagy also forms a Mg ion-dependent

also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation

It interacts with CDC25 phosphatases

Certain mutations in this gene are known to cause distinct forms of muscular dystrophy

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter

NCoA-5 Polyclonal Antibody, 100ul Apoptosis & Autophagy also forms a Mg ion-dependentNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this