Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies secreted proteins lacking transmembrane and

secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling

This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression

Mutations in this gene have been associated with dystonia

Contains 2 RanBD1 domains

Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies secreted proteins lacking transmembrane andITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3