Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays May play a role in

May play a role in cell cycle checkpoint control

Tango1 subfamily

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Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures

Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays May play a role inNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.