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DBLOH Polyclonal Antibody, 50ul Filtration and also associates with eukaryotic

SKU: 5969892054

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DBLOH Polyclonal Antibody, 50ul Filtration and also associates with eukaryoticThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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Description

and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase

The peptide binding cleft accommodates peptides of 10-30 residues

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

DBLOH Polyclonal Antibody, 50ul Filtration and also associates with eukaryoticThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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