WFKN2 Rabbit Polyclonal Antibody, 20ul Protein Modification The A-kinase anchoring protein 11

The A-kinase anchoring protein 11 is expressed at high levels throughout spermatogenesis and in mature sperm

Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage

Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

WFKN2 Rabbit Polyclonal Antibody, 20ul Protein Modification The A-kinase anchoring protein 11The WFIKKN1 protein contains a WAP domain follistatin domain immunoglobulin domain two tandem Kunitz domains and an NTR domain. This gene encodes a WFIKKN1 related protein which has the same domain organization as the WFIKKN1 protein. The WAP type follistatin type Kunitz type and NTR type protease inhibitory domains may control the action of multiple types of proteases.