NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles Two alternative transcripts encoding different

Two alternative transcripts encoding different proteins have been described

It has also been implicated in the progression of several cancers

DVL2 encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein

subcellular location:In ciliated cells

NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles Two alternative transcripts encoding differentThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several