FXL12 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Histone deacetylase 6 encoded by

Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family

Mutations in this gene cause congenital heart defects| multiple types| 2 (CHTD2)

In addition| a single-subunit isoform of this enzyme is found in serum

and intranuclear transport

FXL12 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction Histone deacetylase 6 encoded byMembers of the F box protein family such as FBXL12 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004