GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos laminin receptor 1

laminin receptor 1

This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan

The encoded protein functions as either a homodimer or as a heterodimer with similar family members

with the exception of the B-cell expressed SIGLEC6 (MIM 604405)

GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos laminin receptor 1The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.