IRF-3 Polyclonal Antibody, 20ul[BT-AP04627] Shakers Chromosomal rearrangements and altered expression

Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis

Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes

IRF-3 Polyclonal Antibody, 20ul[BT-AP04627] Shakers Chromosomal rearrangements and altered expressionIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed