syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology Alternative splicing results in four

Alternative splicing results in four transcript variants encoding the same protein

These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain

The encoded protein regulates signaling pathways that affect cell proliferation and adhesion

but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3

syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology Alternative splicing results in fourThe protein encoded by this gene was initially identified as a molecule linking syndecan mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic C terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal membrane organization cell adhesion protein trafficking and the activation of transcription factors. The protein is primarily localized to