GDF-9 Polyclonal Antibody, 100ul[BT-AP03536] Sealing Film Mutations in this gene may

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

The product of CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways

This protein is an essential element of the cyclin A-CDK2 S-phase kinase

Thus| it is thought that this gene may have multiple roles in signal transduction during development

GDF-9 Polyclonal Antibody, 100ul[BT-AP03536] Sealing Film Mutations in this gene mayGDF9 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. Growth differentiation factor 9 regulates ovarian function. Reduced